Skin penetration enhancer
So if you think penetration enhancers in skincare are doing far more to your body than treating surface layers of the skin, then by all means be wary, but please be aware, penetration enhancement is also not black and white. Success of the transdermal route depends on the ability of drugs to breach this barrier and permeate the skin at a rate sufficient to attain effective plasma concentration. INTRODUCTION In recent years the potential of using skin as an alternative route for administering systemically active drugs has received considerable interest and the best way to administer drugs through skin is transdermal patch. Furthermore, with all the research I have combed over in past few years including these latest studies above, molecular size of ingredients prevent most cosmetic and skincare products from going beneath the immediate skins surface without help to achieve penetration of the stratum corneum. Primarily Based On Theory And Not Grounded In Science Unfortunately, we can still locate in many forums or blogs, or even hear from concerned customers on these subjects, about information they stumbled across that is typically prefaced with a firm anti chemical belief. I could not find a single study that actually determined the penetration of the blood brain barrier with cosmetic ingredients utilizing penetration enhancers, only the scare mongering and supposition perpetuated by EWG and CFSC without any peer reviewed studies to substantiate their claims.
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Penetration Enhancers- Which ones to use?
I wanted to stick with 'natural origin' ingredients I know you cringe when someone says that: I do love research! All jokes aside, especially thanks for this post. Where do you think some of the larger companies get these genius marketing ideas? Sign In or Register to comment. The skin has evolved to prevent excessive water loss from the internal organs and to limit the ability of xenobiotics and hazardous substances to enter the body. I work everyday with Cosmetic Entrepreneurs to get their products into the Market.
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Skin penetration enhancers. - PubMed - NCBI
Anything more than that introduces an unacceptable health risk, in my opinion. Where known, the mechanisms of action of these compounds are also discussed. Potential pathways for CPEs to exert their action are examined with reference to the physical chemistry of passive skin transport. I have not come across alpha bisabolol but I will look into it. I was not aware oleic acid is a penetration enhancer
Skin penetration enhancers.
Description: Ordinarily, I'd stay out of a discussion like this. Anything more than that introduces an unacceptable health risk, in my opinion. Newer Post Older Post Home. National Center for Biotechnology Information , U.
Views: 2946 Date: 21.09.2017 Favorited: 5